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For more than 10 years, Novasep Process has been designing, building and selling optimized Prochrom® biochromatography columns and systems for your biopharma purification applications. |
Capture and purification of
Using, for example, affinity, ion exchange, hydrophobic interaction chromatography media.
Standard Model Catalog Numbers
| Low Pressure | Medium Pressure | Max Bed Volume (L) |
| LP.200.500XX5 | MP.200.500 VE20 | 10 |
| LP.300.500XX5 | MP.300.500 VE20 | 25 |
| LP.450.500XX5 | MP.450.500 VE20 | 50 |
| LP.600.500XX5 | MP.600.500 VE20 | 100 |
| LP.800.500XX5 | MP.800.500 VE20 | 180 |
| LP.1000.500XX5 | MP.1000.500 VE20 | 270 |
| LP.1200.500XX5 | MP.1200.500 VE20 | 400 |
XX for either :
- VE: Dynamic Axial Compression
- MO: Manually Operated Piston

-simple
-column up to 80 cm i.d.
Features |
Benefits |
| Pack & unpack in place features | Fast and easy column packing and unpacking in a closed contained system, maintaining optimal conditions for flow distribution |
| Pressure rating: low pressure columns (bar): up to 5 medium pressure columns (bar): from 5 to 20 | Application of a wide range of bioprocessing media, high flow rates |
| Column diameter (mm): from 200 to 2000 | Scale-up guaranteed |
| Bed height (mm): from 20 to 500 | Flexibility for various applications |
| Jack at the top or at the bottom | Flexible design depending on customer and process requirements |
| Uniform flow distribution devices | High separation performance |
| Materials of construction: 316 L stainless steel, acrylic, glass: borosilicate type I, hastelloy, Teflon® seal (compatible with all organic solvents) or EPDM - full material certification package | High quality materials, which allow for a wide range of applications, compatible with all common process solutions |
| Safety & ergonomic tools | Easy to operate and maintain |
| Sanitary fittings, internal finish better than 0.4 µm, electropolished | Sanitary design, "clean solution" |
Novasep Process engineers can design customized units incorporating columns up to 2000 mm internal diameter, ideally suited to your facilities and specific process needs.
Hipersep® Bio Liquid Handing Systems can handle flexible number of buffers & CIP inlets and up to 10 fractions.
Hipersep® Bio |
S |
M |
L |
XL |
Flow rate (L/h) |
15 - 150 |
50 - 500 |
150 - 1500 |
300 - 3000 |

Smart Fraction Collection System
Quality
For Prochrom® Columns:
For Hipersep® Bio:
The Hipersep® SE-Bio software operates and monitors all LPLC and MPLC systems according to customers' needs:
Novasep Process offers complete process development services, and provides performance guarantees for processes supplied.
For more than 10 years, Novasep Process has been designing, building and selling optimized Prochrom® biochromatography columns and systems for your biopharma purification applications.
Novasep Process provides product and process development and fully-automated chromatographic systems that integrate easily and perfectly in your process.
LPLC and MPLC systems incorporate Prochrom® biochromatography columns with bed volumes from 10 to 400 L and column diameter from 200 mm to 2000 mm. We can develop custom-made design on request.
We provide Prochrom® biochromatography columns for your scale-up solution.
Unique teams of chemists, biochemists, process and computer engineers combine their complementary talents to develop and continuously improve therapeutic products capture and purification.
Browse our biopharmaceutical applications
Download our brochure on preparative low and medium pressure chromatography for biopharmaContacts
Europe: biopharma@novasep.com
India:biopharma@novasep.com
Japan: japan@novasep.com
Asia: china@novasep.com