Pharmaceuticals: Novasep Purification, Separation & Production Solutions

The Pharma business unit of Novasep Process offers separation, isolation, purification and production solutions to the pharmaceutical industry for Active Pharmaceutical Ingredients and Advanced Intermediates.

Almost any molecule can be purified or separated with Novasep Process Pharma solutions.

 

Novasep Process pharmaceutical solutions apply more especially to:

• separation of enantiomers of chiral molecules
• purification of peptides (synthetic and non synthetic)
• isolation of natural products
• purification of crude synthetic mixtures

Regarding Chiral molecules...
Regarding peptides...

Novasep Process chromatography systems and services are suitable for :

• laboratory scale pharmaceutical purification
  (R&D, early development, development, pre-clinical step)
• industrial scale pharmaceutical production
  (phase 1, phase 2, phase 3, commercial production)

Novasep Synthesis also offers solutions to pharmaceutical companies via its exclusive synthesis services.

More about Novasep synthesis and production applications for pharmaceuticals.

More about Novasep purification and synthesis solutions for pharmaceuticals.

A long-term partnership

Novasep Process pharma business unit can help pharmaceutical companies from development to production step : pre-clinical phase, clinical phase, commercial phase.

Novasep Process methodology

For many years, Novasep Process has been performing the complete development and optimization of separation/purification processes in its facilities (feasibility studies at laboratory scale, then scale up at pilot scale, validation, etc.).

Novasep Process designs, builds, installs and qualifies the production unit, or performs the custom purification in its facilities (from grams to dozens of tons scale). This capability is complemented by the total synthesis and custom manufacturing capabilities of Novasep Synthesis.

Achievements and references

Novasep Process has installed more than 1,000 purification systems around the world, from lab to large industrial scale. Novasep Process has installed many manufacturing units of APIs in Europe, in USA and in Asia.

Novasep has also designed and commissioned the first, as well as the largest continuous chromatography plants (Simulated Moving Bed and Varicol® systems) in the world, dedicated to the separation of pharmaceutical optical isomers, including Keppra®, Cipralex®/Lexapro® and several others.

The expertise of Novasep Process has also supported the development of numerous molecules and APIs and contributed to their launch on the market (such as the wakefullness-promoting agent Nuvigil®, the anti-depressant Cipralex®/Lexapro®, the anti-cancer Paclitaxel, steroids (multiple applications), and many others (insulins, antibiotics, anti-virals, anti-rejection, anti-HIV, anti-epileptic, anti-cholesterol, etc.).