Prochrom® DAC Columns for Preparative Chromatography Units

The Heart of the Preparative Chromatography Unit

Novasep preparative systems are based on Prochrom® DAC (Dynamic Axial Compression) columns. Over 20 years of experience have been accumulated in the design of Prochrom® DAC columns.

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Pack-n-Sep™ Principle

Pack-n-Sep™ combines the advantages of both Prochrom® columns and an ultra fast packer.

You only need one packer for several columns, of 50 or 80 mm i.d.

Columns can be used on the packer in DAC mode or detached, a unique patented compression device maintaining bed compression.

This packer enables packing or unpacking in less than 5 minutes.

 

Prochrom® Columns Standard Product Line

HPLC

Columns i.d. (mm)	50	80	110	150	200	300	450	590	800	1000	1600
Max bed lengh PV (mm)	350	400		450
Pressure rating (bar)	100			70
Compression features	Dynamic axial compression (DAC)

SFC

Columns i.d. (mm)	50	80	100	150	200
Max bed lengh PV (mm)	350		450
Pressure rating (bar)	300		350
Compression features	DAC

Pack-n-Sep™

Columns i.d. (mm)	50 / 80
Packer	Single packer for both columns sizes
Packed bed length (mm)	10-130	210-270
Pressure rating (bar)	100
Compression features	DAC or static compression

Beyond the above standard column range, we also design and manufacture special columns Please contact us for customized columns.

 

Features & Benefits

Our Offer	Technical Features	Your Benefits
Broadest range of preparative columns on the market	Column i.d.: From 50 to 2000 mm Bed Height: From 200 to 700 mm Pressure: From 5 to 350 bar Complete range of construction materials Several options such as cooling jacket Custom design	Find the column you are looking for! Novasep customizes the column to fulfill your requirements
Optimum column performance	Dynamic Axial Compression (DAC) Smart piston to maintain a constant pressure Robustness of the columns Uniform flow distribution Same design from 50 to 2000 mm column i.d. Optimal separations	Reliable and long lasting columns Guaranteed scale-up and performance
User-Friendly design	Packing and unpacking in place Pack-n-Sep™ Ergonomic tools	Fastest and safest handling
Optimum separation efficiency	Fully automated system Performance qualification Process development services Proprietary simulation tools	Optimum productivity and performance Guaranteed efficiency from the very start Linear scale-up from lab to industrial

As users of our chromatographic systems, we understand your challenges and share our experience and know-how to provide you the best solution.

Options

• Manually operated piston
• Smart piston: protects from over-pressurization of packed beds
• Thermostated jacket: temperature controlled processes
• Electropolishing for easy cleaning and increased lifetime of piston seals
• Ergonomic tools: Extraction arm for the flange, quick connect clamps to disconnect the flange
• Bed and pressure measurement systems
• Packing and unpacking in place
  

Benefits & Advantages

Robustness

Novasep masters the design, manufacturing and installation of reliable preparative and process-scale chromatography columns. Novasep Prochrom® columns are acclaimed for their durability: Prochrom® columns installed in the early 1980's are still in use and producing APIs and biopharmaceuticals. We guarantee the performance and robustness of both our systems and processes.

Product Range

Novasep provides columns adapted to your needs. Novasep Prochrom® chromatography columns offer a range of internal diameters from 50 mm up to 2 m with a customizable column length. Moreover we specifically design systems according to your separation and process requirements. Our broad range of products enables you to find the perfect solution to your separation.

Experience

Novasep has:

• More than 30 years of experience in column design and manufacturing.
• More than 150 engineers continuously improving systems for an increased reliability.
• More than 1500 columns purifying APIs and intermediates everyday, all around the world.
• Thousands of satisfied users.
  

Other

Please challenge us!