Novasep
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Kerasep®-Bio : Modules and Systems for Ceramic TFF Membranes

More than 20 years of experience in TFF

For more than 20 years, we have been designing, building and selling optimized ceramic TFF systems for biopharmaceutical and other life science applications.

We offer Tangential Flow Filtration systems (TFF) from ultrafiltration to microfiltration.

 

Our Systems for Improving the Separation of your Biopharmaceuticals

Experience:

We provide filtration modules and systems from lab to industrial scale, process development including computer modelling and engineering, allowing easy and mastered process integration.

Solution for tough processes:

We offer tangential flow filtration modules and systems from ultrafiltration to microfiltration incorporating ceramic membranes especially adapted to bio-applications requiring operations in difficult conditions (high temperature, pH, high solvent concentrations, etc.)

Commitment:

At Novasep, teams of chemists, biochemists, process and computer engineers combine their complementary talents to develop and continuously improve our systems for the separation of your biopharmaceuticals.

Typical Applications for Tangential Flow Filtration Membranes

Modules and systems incorporating ceramic membranes are ideally suited to the following downstream processing needs:

  • Concentration,
  • Purification,
  • Extraction,
  • Buffer exchange of:
    • Cell cultures
    • Viruses
    • Endogenous/exogenous cell compounds
    • Proteins
    • Polysaccharides

Kerase®-Bio Module and Systems Line

Name of
module

K01 K07 K19

Number of Kerasep® membranes

1 7 19

Number of channels
per membrane

7 8 19 44 7 8 19 44 7 8 19 44

Filtration area (m2)

0.15 0.21 0.25 0.50 1.08 1.47 1.72 3.5 2.95 4.00 4.65 9.50

Name of
module

K37 K99 K138

Number of Kerasep® membranes

37 99 138

Number of channels
per membrane

7 8 19 44 7 8 19 44 7 8 19 44

Filtration area (m2)

5.70 7.80 9.10 18.5 15.3 20.8 24.3 49.5 21.4 39 33.8 69.0

 

Kerasep® Modules:

  • 1 to 138 membranes
  • Compact, sanitary design

Kerasep® TFF Systems:

We offer several types of filtration systems from nanofiltration to microfiltration, from semi-automated to fully automated. We guarantee a sanitary, ergonomic and compact design while providing validated software compliant with 21 CFR part 11 and GAMP 4. All our systems are cGMP compliant and are built according to the current ASME-BPE code of construction.

Modules Description:

  • Carter: 316 L stainless steel quality
  • Gaskets: Silicone, EPDM, Viton, Kalrez
  • Sanitary fittings, internal finish better than 0.4 µm, electropolished

Connections:

Tri-clamp sanitary connections

Options

  • Design for ATEX zone
  • CIP/SIP
  • Solvent recovery systems

We also design and sell reliable ceramic Kerasep® Bio membranes.

Download our brochures for biologics manufacturing.

For any questions on Novasep's purification/separation services and equipment for biologics, please contact us.

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