Synthesis and Purification Technologies

A unique palette for the efficient manufacturing of your synthetic molecules.

Technologies for Synthetic Molecules Manufacturing

Novasep masters a unique palette of technologies for the efficient synthesis of your APIs, agrochemicals, cosmetics, and specialty chemicals, from kilogram to multi-ton scale.

Chiral technologies

• Asymmetric synthesis: diastereoselective  synthesis, asymmetric catalysis, other enantioselective reactions
• Chiral resolution: chiral chromatography, enzymatic resolution, chemical resolution, kinetic and dynamic kinetic resolution, preferential crystallization
• Chiral pool.

Hazardous chemistry

• Azide, diborane, diazomethane, hydrazine, carbon disulfide, and nitroalkane chemistry
• Ozonolysis, carbonylation, cyclopropanation,  oxidation with O2, hydrogen peroxide oxidation, sodium metal handling
• Handling of thermally and mechanically instable compounds as well as highly toxic materials, ability to perform highly exothermic reactions.

Highly potent APIs

• Total synthesis, semi-synthesis, extraction, purification, vectorization.

Advanced organic synthesis

• Cryogenic reactions, Friedel Craft reactions, micro-reaction technologies, transition metal catalysis, organometallic chemistry, hydrogenation, halogenation, heterocyclic chemistry, Mitsunobu reactions, biocatalysis, semi-synthesis.

Preparative chromatography

• High Performance Liquid Chromatography (HPLC), Supercritical Fluid Chromatography (SFC), multi-column continuous chromatography (Varicol®, simulated moving bed (SMB)), Medium and Low Pressure Chromatography (LPLC, MPLC).

Advanced purification technologies

• Crystallization and polymorphism control, distillation, membrane filtration (nano-, ultra-, micro-filtration), spray drying.

Download our brochures for synthetic molecule manufacturing.

Contact us  for any synthetic molecule manufacturing request.