Chiral Chromatography

Chiral Chromatography Solutions by Novasep Process

Novasep Process has developed a unique know-how and a pool of technologies in the field of chiral separation and chemical purification for the pharmaceutical industry. We offer:

• Batch chromatography (HPLC and SFC)
• Continuous chromatography (Varicol®)
• Process developement and scale-up
• Process validation
• Kg to ton scale separation
• Custom separation from pre-clinical to commercial phases.

What's New in Large-scale Chiral Chromatography?

Chiral chromatography has entered into a new era. Industrial chromatography is performed on automated, proven equipment, combining speed, robustness, cost-efficiency and manufacturing versatility. Over the past few years, large-scale chiral chromatography has become an essential tool for the pharmaceutical industry. Early adopters have significantly reduced their time to market and have brought APIs to 100 multi-tons scale using cost efficient commercial chromatography processes.

mid-1950s Photo courtesy of the FDA History Office

Nowadays

Left: A chemist is shown using a preparative column chromatographic apparatus in the mid-1950s.
Right: A contemporary continuous chromatography Varicol® 6 x 200 mm system used for a chiral resolution.

A pioneer in continuous chromatography, Novasep is recognized as the world leader in preparative and large-scale chiral chromatography. Our customers can combine the experience of Novasep Process in designing and operating industrial chiral chromatography processes and technologies with the experience of Novasep Synthesis to bring the most cost-efficient global chiral synthesis to reality. Novasep is an ideal partner for your chiral resolutions.

We can either rapidly develop an optimised process and use our own chromatography facilities to speed your product to market or we can build a versatile chromatography unit to install at your own site. The choice is yours.

Novasep and Daicel/Chiral Technologies signed an agreement combining our expertise in process development and theirs in CSP. This cooperation ensures that your process in optimally developed for a guaranteed performance.

 

We welcome your development challenge!
Our experience will always make the difference!