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Blood and plasma are complex mixtures from which therapeutic proteins are purified. Traditional processes use Cohn fractionation. A changing market landscape requires the implementation of new purification technologies with higher efficiency, cost-effectiveness and ease of automation.
Novasep provides best-in-class purification equipment and process development services for your plasma-derived therapeutics production workshop.
Whether you want to recover clotting factors, fibrinogen, poly-IgG, specific IgG or α1-antitrypsin, etc., several chromatography steps can be used to reach high purity and quality.
Prochrom®-Bio is a range of industrial chromatography columns from 150 up to 1,600 mm I.D. and associated fluid management systems.
Fully automated, Prochrom®-Bio LPLC allows reproducible and easy operations.
Thanks to a smart design of the piston technology, the columns are easy to operate, clean and maintain.
Our packing technology brings unique value to your chromatography step:
Learn more about the Prochrom®-Bio technology.
BioSC™ technology addresses many plasma fractionation constraints.
Cut down your manufacturing costs by:
Purify the same volume of plasma with a smaller system compared to batch chromatography.
Significantly reduce processing time by 2 to 4-fold, which is particularly critical for labile components such as Factor VIII.
Learn more about the BioSC™ technology.
Tangential flow filtration is commonly used in plasma fractionation processes to purify, concentrate or formulate plasma-derived products. Novasep can provide you with customized industrial TFF systems for high performance and robust operations.