We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we'll assume that you are OK with this.     OK  No, I would like to know more...
Case Study ADC Fast Track Novasep

Case study: Generation of first ADC samples for preclinical studies

 

 

ADC Fast Track Case Study Novasep

 

 

Having identified a novel Antibody Drug Conjugate asset, pharmaceutical companies often have the capacity to synthesize R&D samples internally, but few of them have the dedicated facilities to produce larger quantities. They need to find a reliable CDMO partner that can manufacture their ADC sample to support their preclinical development program.

Novasep was approached by a biopharmaceutical company developing a preclinical ADC sample consisting of IgG1 mAb conjugated with a proprietary payload. The customer needed a larger amount of ADC in order to launch a pre-toxicology study.

 

Highlights:

>  Phase adapted ADC characterization using Novasep's platform methods 
>  Process optimization and scale-up for pre-toxicology study
>  Recommendations for further process & analytical development

 

 

 

 

Download Now
 
 
Thank you for your submission ! You can now download your file by clicking on the button below: Case study: Generation of first ADC lead candidates at lab scale to support pre-toxicology development program