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Purification processes for amino-acids
Fermentation & bio-based

Purification processes for amino-acids


Working for more than 30 years in the fermentation industries, Novasep has developed a specific expertise for designing and commissioning amino-acids process lines.

Novasep Amino Acids For Animal FeedingNovasep has extensive experience regarding the following amino-acids:

  • MSG
  • Lysine
  • Threonine
  • Aromatic amino-acids: tryptophan, phenylalanine, etc.
  • Other specialty amino-acids such as leucine, etc.
    Novasep Lysine Manufacturing Process

Novasep’s cross-flow filtration technology, based on Kerasep® ceramic membranes and modules provides our customers with robust and cost-effective clarification solutions. Our Kerasep® ceramic membranes are the industrial reference for broth clarification, with an unrivalled, guaranteed operational lifetime.

Novasep’s Applexion™ continuous ion exchange technology enables customers to optimize amino-acid recovery (up to 99%), and quality before drying. Compared to a traditional batch processing, continuous ion exchange, dramatically decreases process operation costs and increases ROI:

  • Amino-acid is more concentrated, reducing the load on the concentration step
  • Reduced water and chemicals consumption
  • Reduced effluent generation
  • Reduction of resin volume

Novasep Threonin Manufacturing ProcessFor additional amino-acid refining (e.g. aromatic amino acid) Novasep is able to propose SSMB chromatography technology. SSMB can significantly improve amino-acid recovery by recycling mother liquor following centrifugation (patent pending). It can desalt very efficiently specialty amino acids-containing solutions, like leucine and glycine for example.

To further reduce operational costs Novasep can also provide highly optimized evaporation and crystallization solutions. According to your feed properties and targeted capacity, we are able to optimize your CAPEX/OPEX balance by designing the optimum technology combination with minimized energy consumption.


Thanks to Novasep’s recognized project management methodology, we are able to provide customers with the best process solution in a cost-effective and timely manner. Our process development expertise enables us to guarantee the performance of your final industrial process.

Novasep has engineering capability in Europe, Asia and North America, which enables us to support projects in any location of the world. In addition we offer global audits and process improvement services, to ensure continued process optimum performance is maintained and offer rapid resolution to local issues.

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