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Our Prochrom®-Bio low pressure chromatography columns and systems provide highly reliable and robust solutions, designed for industrial processes and heavy duty operations.
The range, very complete with lab- to large-scale equipment, includes:
Prochrom®-Bio is a smart chromatography solution for biopharmaceuticals applications such as:
Our low-pressure chromatography columns are designed for convenience and high-performance:
Our columns can be customized upon request.
Because chromatography is an important and ubiquitous unit operation in downstream bioprocessing, FDA inspectors are showing an increased interest in the reproducible packing characteristics of chromatography columns. Novasep provides two efficient packing systems, depending on the size of the column.
For pilot-scale columns (150 – 300 mm), Elemental packing reduces the tasks and the number of units to their strict minimum without compromising packing performance.
Prochrom®-Bio Automated packing units bring true advantages to the user by optimizing media slurry injection and minimizing time outside of manufacturing steps. Combining the packing unit with Prochrom®-Bio column from 450 to 1600 mm provides the following benefits during packing, repacking in place and unpacking operations:
Hipersep®-Bio systems are automated low-pressure buffer delivery modules for preparative chromatography in cGMP biopharmaceutical environments. These systems manage injection (buffer, product, etc.) into the chromatography column; detection and collection of the target fractions.
In combination with our Prochrom®-Bio columns, you get the best from low-pressure chromatography.
Typical ColumnI.D. (mm)
Our equipment includes advanced Process Analytical Technologies compliant with the FDA PAT guidelines, such as a high performance in-line dilution module, as well as smart fraction collection software, and a column back-flush valve enabling elution direction reversal into the column.
Hipersep®-Bio systems can be customized to meet specific needs, including:
Our in-line dilution technology enables our customers to directly prepare buffer from water and concentrated buffer solutions. This approach presents several benefits including:
Our in-line mixing technology can be integrated in our technologies. It can also be supplied as a stand-alone unit (optional). This equipment is custom made depending on your process and requirements. Please contact us to learn more.